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Writer's pictureGenny Mack

Japanese Knotweed and Lupus: Can Resveratrol Help Alleviate Symptoms?

Lupus, a chronic autoimmune disease, affects millions worldwide, especially women and communities of color. While conventional treatments are essential to stabilize the disease, natural plant medicines like Japanese Knotweed may offer additional support. This post explores how Resveratrol in Japanese knotweed may benefit those with lupus.


black woman with lupus
Black Woman with Lupus

The Power of Resveratrol


Resveratrol, a polyphenol found in Japanese Knotweed, has gained attention for its potential health benefits. Japanese Knotweed, known as Fallopia Japonica, is native to Japan (of course), China and parts of Korea and Taiwan. This powerful antioxidant has anti-inflammatory and immune-modulating properties, making it a promising adjunct for lupus management.


Now you may be thinking, “Where did I hear about Resveratrol?” Probably in red wine, because the skin of grapes has Resveratrol. That's why people say drink a glass a day. But imagine gaining the effects of Reservatrol, without the effects of alcohol?


Guess what? Japanese Knotweed, has a more bio-active concentration of Reservatrol than in grapes. That compound found in Japanese Knotweed is called Trans-Resveratrol, which means that it is more potent.


japanese knotweed and lupus resveratrol
Japanese Knotweed containing Resveratrol

I first discovered Japanese Knotweed on a foraging exploration in 2022, while discovering the natural medicine that Mother Nature has to offer.  Now, I anticipate its arrival during the spring time when flowers start to blossom and leaves begin to illuminate its green chlorophyll.  The stalks are edible, and taste like a cross between a rhubarb and asparagus. I love to make a fresh Japanese Knotweed Compote in April and May of each year and drizzle it on top of yogurt or oatmeal. Absolutely delicious.


But Japanese Knotweed gets bad rep because it is quite invasive, similar to Bamboo, and can even cause destruction to structures. My husband once told me that he spent a day of digging out Japanese Knotweed roots in his friend’s backyard in the UK because one can actually be prosecuted if it becomes a nuisance because of the damages that it can cause. Fascinating. Why? Because it tells me how strong Japanese Knotweed is, especially the roots.


Now, let’s talk about how powerful Japanese Knotweed is. 


yogurt bowl with japanese knotweed compote resveratrol
Yogurt Bowl with Japanese Knotweed Compote

Potential Benefits for Lupus Warriors:


1. Reduced Inflammation: Resveratrol's anti-inflammatory properties may help alleviate joint pain, swelling, and fatigue associated with lupus flares.


2. Immune System Regulation: Resveratrol may help modulate the immune system's response, T-cells specifically, and activate natural killer cells to reduce pro-inflammatory cytokines, thus reducing the risk of autoimmune flares.


3. Antioxidant Protection: Resveratrol's antioxidant properties can help shield cells from damage caused by oxidative stress, a common issue in lupus. It has been studied to kill cancer cells, too!


4. Cardiovascular Health: Resveratrol may help reduce the risk of cardiovascular disease, a common comorbidity in lupus patients.


Japanese Knotweed is available via capsules, powders and tinctures.



japanese knotweed  young shoot
Young Japanese Knotweed Shoot

Disclaimer: Consult with your healthcare provider before adding Japanese knotweed supplements to your regimen. This is not medical advice. This information is not meant to give advice to treat, cure or prevent any disease. Like with any plant medicine, it can have contraindications to pharmaceutical medications. Do your own research!


While Japanese knotweed is not a replacement for conventional lupus treatment, Resveratrol may offer complementary benefits. By understanding the potential of this natural supplement, lupus warriors can make informed decisions about their health. Always consult with a healthcare professional before adding new supplements to your routine.


Did you find this article helpful? Let know what you think about Japanese Knotweed!


In Love in Good Health,


Genny Mack




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